Distribuição de tipos moleculares de Cryptococcus gattii no Brasil: uma revisão bibliográfica
DOI:
https://doi.org/10.51723/ccs.v27i02.97Keywords:
Cryptococcus gattii, Cryptococcus, cryptococcosisAbstract
Objective: Describe the distribution of Cryptococcus gattii molecular types in Brazil by reviewing studies published until 2016.
Source of data: Review of studies published until 2016 in the DeCS‑BVS site in Portuguese, English or Spanish. The inclusion criterion was description of molecular typing of C. gattii isolates obtained in Brazil. Manuscripts without full text and without molecular information on C. gattii were excluded.
Synthesis of the collected data: We have included ten publications ranging from 2008 to 2016 containing information about the molecular characterization of C. gattii isolates from the four geographic regions of Brazil.
Conclusions: C. gattii is endemic in the North and Northeast regions of Brazil, but can also be found in the other regions. The predominant molecular type was VGII, accounting for about 80% of the cases. VGII has very high genetic variability. VGII isolates from the Northeast region are distinct from those found in the North.
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References
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6. Meyer W, Castaneda A, Jackson S, Huynh M, Castaneda E and the Ibero American Cryptococcal Study Group (2003): Molecular typing of Ibero American Cryptococcus neoformans Isolates, Emerging Infect. Dis.: 9(2):189‑195. 44
7. Boekhout T, Theelen B, Diaz M, Fell JW, Hop WCJ, Abeln ECA, Dromer F, Meyer W. Hybrid genotypes in the pathogenic yeast Cryptococcus neoformans. Microbiology.2001; 147:891‑907
8. Meyer W, Aanensen DM, Boekhout T, Cogliati M, Diaz MR, Esposto MC, et al. Consensus multi‑locus sequence typing scheme for Cryptococcus neoformans and Cryptococcus gattii. Med Mycol. 2009; 47:561–570.
9. Hagen F, Khayhan K, Theelen B, Kolecka A, Polacheck I, et al. (2015) Recognition of seven species in the Cryptococcus gattii/Cryptococcus neoformans species complex. Fungal Genet Biol. doi: 10.1016/j.fgb.2015.02.009
10. Meyer W, Gilgado F, Ngamskulrungroj P, Trilles L, Hagen F, Castañeda E et al. Molecular typing of Cryptococcus. In Cryptococcus: from human pathogen to model yeast. ASM Press. 2011. p. 327‑358.
11. Trilles L, Lazéra MS, Wanke B, Oliveira RV, Barbosa GG, Nishikawa MM et al . Regional pattern of the molecular types of Cryptococcus neoformans and Cryptococcus gattii in Brazil. Mem. Inst. Oswaldo Cruz [Internet]. 2008 Aug [cited 2016 Aug 15]; 103( 5 ): 455‑462.
12. Santos WRA, Meyer W, Wanke B, Costa SPSE, Trilles L, Nascimento JLM et al . Primary endemic Cryptococcosis gattii by molecular type VGII in the state of Pará, Brazil. Mem. Inst. Oswaldo Cruz [Internet]. 2008 Dec [cited 2016 Aug 15]; 103( 8 ): 813‑818.
13. Costa, SPSE. Isolamento e caracterização molecular de Cryptococcus neoformans e Cryptococcus gattii de fontes ambientais na região metropolitana de Belém, Pará / Solange do Perpétuo Socorro Evangelista Costa. – Rio de Janeiro, 2008. xviii, 161 f. : il. ; 30 cm. Tese (doutorado) – Instituto Oswaldo Cruz, Pós‑Graduação em Biologia Parasitária, 2008.
14. Luvizotto MCR, Carreira VS, Ferrari HF, Ribeiro D, Vallim MA, Azevedo V et al . Brain and lung cryptococcoma and concurrent corynebacterium pseudotuberculosis infection in a goat: a case report. J. Venom. Anim. Toxins incl. Trop. Dis [Internet]. 2009 [cited 2016 Aug 15] ; 15( 3 ): 553‑561.
15. Costa SPSE, Lazéra MS, Santos WRA, Morales BP, Bezerra CCF, Nishikawa MM et al . First isolation of Cryptococcus gattii molecular type VGII and Cryptococcus neoformans molecular type VNI from environmental sources in the city of Belém, Pará, Brazil. Mem. Inst. Oswaldo Cruz [Internet]. 2009 July [cited 2016 Aug 15] ; 104( 4 ): 662‑664.
16. Pinto Junior V L, Pone MVSilva, Pone SM, Campos JMS, Garrido JRP, Barros ACMW et al . Cryptococcus gattii molecular type VGII as agent of meningitis in a healthy child in Rio de Janeiro, Brazil: report of an autochthonous case. Rev. Soc. Bras. Med. Trop. [Internet]. 2010 Dec [cited 2016 Aug 15] ; 43 ( 6 ): 746‑748.Junior JL et al.
17. Martins LMS, Wanke B, Lazéra MS, Trilles L, Barbosa GG, Macedo RCL de et al. Genotypes of Cryptococcus neoformans and Cryptococcus gattii as agents of endemic cryptococcosis in Teresina, Piauí (northeastern Brazil). Mem. Inst. Oswaldo Cruz [Internet]. 2011 Sep [cited 2016 Aug 15]; 106( 6 ): 725‑730.
18. Souza LKH, Costa CR, Fernandes OFL, Abrao FY, Silva TC, Tremea CMartins et al. Clinical and microbiological features of cryptococcal meningitis. Rev. Soc. Bras. Med. Trop. [Internet]. 2013 June [cited 2016 Aug 15]; 46( 3 ): 343‑347.
19. Souto, ACP. Analysis of the Variability of VGII genotype of Cryptococcus gattii in Environmental and Clinical Isolates from Brazil. Rio de Janeiro, 2013.
80f. Master [Science dissertation in Clinic Research in Infectious Diseases] ‑ Instituto de Pesquisa Clínica Evandro Chagas.
20. Souto ACP, Bonfietti LX, Ferreira ‑Paim K, Trilles L, Martins M, Ribeiro‑Alves M, et al. (2016) Population Genetic Analysis Reveals a High Genetic Diversity in the Brazilian Cryptococcus gattii VGII Population and Shifts the Global Origin from the Amazon Rainforest to the Semi‑arid Desert in the Northeast of Brazil. PLoS Negl Trop Dis 10(8)
21. Baltazar LM, Ribeiro MA. Primeiro isolamento ambiental de Cryptococcus gattii no Estado do Espírito Santo. Rev. Soc. Bras. Med. Trop. [Internet]. 2008 Oct [cited 2016 Aug 15]; 41( 5 ): 449‑453.
22. Cogliati M. Global Molecular Epidemiology of Cryptococcus neoformans and Cryptococcus gattii: An Atlas of the Molecular Types. Scientifica. 2013; 2013: 1‑23.
23. Chen SC, Meyer W, Sorrell TC. Cryptococcus gattii infections. Clin Microbiol Rev. 2014;27: 980–1024. doi: 10.1128/CMR.00126‑13. pmid:25278580.
24. Espinel‑Ingroff A, Kidd SE. 2015. Current trends in the prevalence of Cryptococcus gattii in the United States and Canada. Infect Drug Resist 8:89–97.10.2147/IDR.S57686.
2. Brouwer AE, Rajanuwong A, Chierakul W, Griffin GE, Larsen RA, White NJ, et al. (2004) Combination antifungal therapies for HIV‑associated cryptococcal meningitis: a randomised trial. Lancet 363: 1764–1767. pmid:15172774 doi: 10.1016/s0140‑6736(04)16301‑0
3. Kronstad JW, Attarian R, Cadieux B, Choi J, D’Souza CA, Griffiths EJ, Geddes JM, Hu G, Jung WH, Kretschmer M, Saikia S, Wang J.Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box. Nat Rev Microbiol. 2011 Mar;9(3):193‑203.
4. Kwon‑Chung KJ, Polacheck I, Bennet JE. Improved diagnostic medium for separation of Cryptococcus neoformans var. neoformans (serotypes A and D) and Cryptococcus neoformans var. gattii (serotype B and C). Journal Clinical Microbiology 115:535‑537, 1982.
5. Meyer W, Marszewska K, Amirmostofian M, et al. (1999) Molecular typing of global isolates of Cryptococcus neoformans var. neoformans by polymerase chain reaction fingerprinting and randomly amplified polymorphic DNA‑a pilot study to standardize techniques on which to base a detailed epidemiological survey. Electrophoresis 20: 1790–1799
6. Meyer W, Castaneda A, Jackson S, Huynh M, Castaneda E and the Ibero American Cryptococcal Study Group (2003): Molecular typing of Ibero American Cryptococcus neoformans Isolates, Emerging Infect. Dis.: 9(2):189‑195. 44
7. Boekhout T, Theelen B, Diaz M, Fell JW, Hop WCJ, Abeln ECA, Dromer F, Meyer W. Hybrid genotypes in the pathogenic yeast Cryptococcus neoformans. Microbiology.2001; 147:891‑907
8. Meyer W, Aanensen DM, Boekhout T, Cogliati M, Diaz MR, Esposto MC, et al. Consensus multi‑locus sequence typing scheme for Cryptococcus neoformans and Cryptococcus gattii. Med Mycol. 2009; 47:561–570.
9. Hagen F, Khayhan K, Theelen B, Kolecka A, Polacheck I, et al. (2015) Recognition of seven species in the Cryptococcus gattii/Cryptococcus neoformans species complex. Fungal Genet Biol. doi: 10.1016/j.fgb.2015.02.009
10. Meyer W, Gilgado F, Ngamskulrungroj P, Trilles L, Hagen F, Castañeda E et al. Molecular typing of Cryptococcus. In Cryptococcus: from human pathogen to model yeast. ASM Press. 2011. p. 327‑358.
11. Trilles L, Lazéra MS, Wanke B, Oliveira RV, Barbosa GG, Nishikawa MM et al . Regional pattern of the molecular types of Cryptococcus neoformans and Cryptococcus gattii in Brazil. Mem. Inst. Oswaldo Cruz [Internet]. 2008 Aug [cited 2016 Aug 15]; 103( 5 ): 455‑462.
12. Santos WRA, Meyer W, Wanke B, Costa SPSE, Trilles L, Nascimento JLM et al . Primary endemic Cryptococcosis gattii by molecular type VGII in the state of Pará, Brazil. Mem. Inst. Oswaldo Cruz [Internet]. 2008 Dec [cited 2016 Aug 15]; 103( 8 ): 813‑818.
13. Costa, SPSE. Isolamento e caracterização molecular de Cryptococcus neoformans e Cryptococcus gattii de fontes ambientais na região metropolitana de Belém, Pará / Solange do Perpétuo Socorro Evangelista Costa. – Rio de Janeiro, 2008. xviii, 161 f. : il. ; 30 cm. Tese (doutorado) – Instituto Oswaldo Cruz, Pós‑Graduação em Biologia Parasitária, 2008.
14. Luvizotto MCR, Carreira VS, Ferrari HF, Ribeiro D, Vallim MA, Azevedo V et al . Brain and lung cryptococcoma and concurrent corynebacterium pseudotuberculosis infection in a goat: a case report. J. Venom. Anim. Toxins incl. Trop. Dis [Internet]. 2009 [cited 2016 Aug 15] ; 15( 3 ): 553‑561.
15. Costa SPSE, Lazéra MS, Santos WRA, Morales BP, Bezerra CCF, Nishikawa MM et al . First isolation of Cryptococcus gattii molecular type VGII and Cryptococcus neoformans molecular type VNI from environmental sources in the city of Belém, Pará, Brazil. Mem. Inst. Oswaldo Cruz [Internet]. 2009 July [cited 2016 Aug 15] ; 104( 4 ): 662‑664.
16. Pinto Junior V L, Pone MVSilva, Pone SM, Campos JMS, Garrido JRP, Barros ACMW et al . Cryptococcus gattii molecular type VGII as agent of meningitis in a healthy child in Rio de Janeiro, Brazil: report of an autochthonous case. Rev. Soc. Bras. Med. Trop. [Internet]. 2010 Dec [cited 2016 Aug 15] ; 43 ( 6 ): 746‑748.Junior JL et al.
17. Martins LMS, Wanke B, Lazéra MS, Trilles L, Barbosa GG, Macedo RCL de et al. Genotypes of Cryptococcus neoformans and Cryptococcus gattii as agents of endemic cryptococcosis in Teresina, Piauí (northeastern Brazil). Mem. Inst. Oswaldo Cruz [Internet]. 2011 Sep [cited 2016 Aug 15]; 106( 6 ): 725‑730.
18. Souza LKH, Costa CR, Fernandes OFL, Abrao FY, Silva TC, Tremea CMartins et al. Clinical and microbiological features of cryptococcal meningitis. Rev. Soc. Bras. Med. Trop. [Internet]. 2013 June [cited 2016 Aug 15]; 46( 3 ): 343‑347.
19. Souto, ACP. Analysis of the Variability of VGII genotype of Cryptococcus gattii in Environmental and Clinical Isolates from Brazil. Rio de Janeiro, 2013.
80f. Master [Science dissertation in Clinic Research in Infectious Diseases] ‑ Instituto de Pesquisa Clínica Evandro Chagas.
20. Souto ACP, Bonfietti LX, Ferreira ‑Paim K, Trilles L, Martins M, Ribeiro‑Alves M, et al. (2016) Population Genetic Analysis Reveals a High Genetic Diversity in the Brazilian Cryptococcus gattii VGII Population and Shifts the Global Origin from the Amazon Rainforest to the Semi‑arid Desert in the Northeast of Brazil. PLoS Negl Trop Dis 10(8)
21. Baltazar LM, Ribeiro MA. Primeiro isolamento ambiental de Cryptococcus gattii no Estado do Espírito Santo. Rev. Soc. Bras. Med. Trop. [Internet]. 2008 Oct [cited 2016 Aug 15]; 41( 5 ): 449‑453.
22. Cogliati M. Global Molecular Epidemiology of Cryptococcus neoformans and Cryptococcus gattii: An Atlas of the Molecular Types. Scientifica. 2013; 2013: 1‑23.
23. Chen SC, Meyer W, Sorrell TC. Cryptococcus gattii infections. Clin Microbiol Rev. 2014;27: 980–1024. doi: 10.1128/CMR.00126‑13. pmid:25278580.
24. Espinel‑Ingroff A, Kidd SE. 2015. Current trends in the prevalence of Cryptococcus gattii in the United States and Canada. Infect Drug Resist 8:89–97.10.2147/IDR.S57686.
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Published
2017-12-27
How to Cite
1.
Júnior JL, Santos IB dos, Pinto Júnior VL, Nicola AM. Distribuição de tipos moleculares de Cryptococcus gattii no Brasil: uma revisão bibliográfica. Com. Ciências Saúde [Internet]. 2017 Dec. 27 [cited 2024 May 21];27(02):159-66. Available from: https://revistaccs.escs.edu.br/index.php/comunicacaoemcienciasdasaude/article/view/97
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